spark therapeutics roche

SOME OF THE STATEMENTS CONTAINED IN THIS ANNOUNCEMENT ARE FORWARD-LOOKING STATEMENTS, INCLUDING STATEMENTS REGARDING, AMONG OTHER THINGS, THE EXPECTED CONSUMMATION OF THE TRANSACTION, WHICH INVOLVES A NUMBER OF RISKS AND UNCERTAINTIES, INCLUDING THE SATISFACTION OF CLOSING CONDITIONS FOR THE TRANSACTION, INCLUDING REGULATORY APPROVAL, THE TENDER OF A MAJORITY OF THE OUTSTANDING SHARES OF COMMON STOCK OF SPARK THERAPEUTICS, THE POSSIBILITY THAT THE TRANSACTION WILL NOT BE COMPLETED, AND OTHER RISKS AND UNCERTAINTIES DISCUSSED IN SPARK THERAPEUTICS’ PUBLIC FILINGS WITH THE UNITED STATES SECURITIES AND EXCHANGE COMMISSION (THE “SEC”), INCLUDING THE “RISK FACTORS” SECTIONS OF SPARK THERAPEUTICS’ ANNUAL REPORT ON FORM 10-K FOR THE YEAR ENDED DECEMBER 31, 2017 AND SUBSEQUENT QUARTERLY REPORTS ON FORM 10-Q, AS WELL AS THE TENDER OFFER DOCUMENTS TO BE FILED BY ROCHE AND ITS ACQUISITION SUBSIDIARY AND THE SOLICITATION/RECOMMENDATION TO BE FILED BY SPARK THERAPEUTICS. He won’t rule out Dyno pursuing its own gene therapies in the future, but he says that the company is also looking for more partners that can help take the company’s technology to more diseases in more parts of the body. At Spark Therapeutics, a fully integrated, commercial company committed to discovering, developing and delivering gene therapies, we challenge the inevitability of genetic diseases, including blindness, hemophilia, lysosomal storage disorders and neurodegenerative diseases. ROCHE AND SPARK THERAPEUTICS DISCLAIM ANY INTENT OR OBLIGATION TO UPDATE ANY FORWARD-LOOKING STATEMENTS AS A RESULT OF DEVELOPMENTS OCCURRING AFTER THE PERIOD COVERED BY THIS REPORT OR OTHERWISE. INVESTORS AND SECURITY HOLDERS MAY ALSO OBTAIN FREE COPIES OF THE SOLICITATION/RECOMMENDATION STATEMENT AND OTHER DOCUMENTS FILED WITH THE SEC BY SPARK THERAPEUTICS AT www.sparktx.com. Additional candidates in Spark Therapeutics' portfolio include SPK-9001, an investigational gene therapy for the potential treatment of hemophilia B in phase III and SPK-7001 for choroideremia in phase I/II. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Click to get this free report, Roche Holding AG (RHHBY): Free Stock Analysis Report, Novartis AG (NVS): Free Stock Analysis Report, Spark Therapeutics, Inc. (ONCE): Free Stock Analysis Report, Amgen Inc. (AMGN): Free Stock Analysis Report. For more information, please visit www.roche.com. Our mission at Spark Therapeutics is to challenge the inevitability of genetic disease by discovering, developing and delivering potential treatments in ways unimaginable—until now. Others may spark an interaction with the immune system. All trademarks used or mentioned in this release are protected by law. Founded in March 2013 as a result of the technology and know-how accumulated over two decades at Children’s Hospital of Philadelphia (CHOP), Spark Therapeutics’ investigational therapies have the potential to provide long-lasting effects, dramatically and positively changing the lives of patients with conditions where no, or only palliative, therapies exist. Die Transaktion wird voraussichtlich im zweiten Quartal 2019 abgeschlossen. For liver disorders or disorders that can be addressed by the production of proteins in the liver, a gene therapy would need to target the cells of that organ. The company also aims to improve patient access to medical innovations by working with all relevant stakeholders. The closing of the transaction is expected to take place in the second quarter of 2019. The most advanced Spark program, SPK-8011, is expected to enter Phase 3 development next year for hemophilia A. Weitere klinische Programme von Spark Therapeutics sind: SPK-9001, eine Gentherapie für die mögliche Behandlung der Hämophilie B in Phase 3, sowie SPK-7001 gegen Choroideremie in Phase 1/2. Greater understanding of the human genome and genetic abnormalities have allowed Spark Therapeutics’ scientists to tailor investigational therapies to patients suffering from very specific genetic diseases. Dyno will use its technology to design capsids and Roche will supply the genetic payloads that they will carry. «Als einziges Biotechnologieunternehmen, das eine Gentherapie gegen eine genetische Erkrankung in den USA erfolgreich auf den Markt gebracht hat, verfügen wir über einzigartige Kompetenzen in der Erforschung, Entwicklung und Bereitstellung von Gentherapien. ROCHE AND SPARK THERAPEUTICS DISCLAIM ANY INTENT OR OBLIGATION TO UPDATE ANY FORWARD-LOOKING STATEMENTS AS A RESULT OF DEVELOPMENTS OCCURRING AFTER THE PERIOD COVERED BY THIS REPORT OR OTHERWISE. node.dataset.value : node.getAttribute('data-value'); if (selectedValue) { for (var j = 0; j < node.options.length; j++) { if(node.options[j].value === selectedValue) { node.options[j].selected = 'selected';break;}}}}}, Do Not Sell My Personal Information (CA Residents Only). Roche’s $4.3 billion buyout of Spark Therapeutics may not be the largest deal by size in 2019, but it’s definitely one of the most closely watched. Das von Spark Therapeutics in den USA vermarktete LUXTURNA® (Voretigene Neparvovec-rzyl) ist eine Gentherapie für die Behandlung von Patienten mit Netzhautdystrophie und bestätigter bialleler Mutation des RPE65 Gens. Closing of the tender offer is conditioned upon customary closing conditions, including the expiration or termination of the applicable waiting period under the Hart-Scott-Rodino Antitrust Improvements Act, and there being validly tendered and received, and not validly withdrawn, a majority of the outstanding Spark Shares. Spark Therapeutics' hemophilia A program could become a new therapeutic option for people living with this disease. Roche is also the world leader in in vitro diagnostics and tissue-based cancer diagnostics, and a frontrunner in diabetes management. Thirty medicines developed by Roche are included in the World Health Organization Model Lists of Essential Medicines, among them life-saving antibiotics, antimalarials and cancer medicines. Under the terms of the merger agreement, Roche will promptly commence a tender offer to acquire all outstanding shares of Spark Therapeutics common stock, and Spark Therapeutics will file a recommendation statement containing the unanimous recommendation of the Spark Therapeutics board that Spark Therapeutics’ shareholders tender their shares to Roche. Severin Schwan, der CEO von Roche, äusserte sich zu der Transaktion wie folgt: «Das ausgewiesene Know-how von Spark Therapeutics in der gesamten Wertschöpfungskette der Gentherapie eröffnet wichtige neue Möglichkeiten für die Behandlung schwerer Krankheiten. Research indicates one sector is poised to deliver a crop of the best-performing stocks you'll find anywhere in the market. Spark Therapeutics is headquartered in Philadelphia, Pennsylvania. Das Unternehmen hat weitere präklinische Forschungsprogramme gegen die Huntington-Krankheit und gegen Morbus Stargardt. Recent trades from this sector have generated +98% , +119% and +164% gains in as little as 1 month. Genentech in den USA gehört vollständig zur Roche-Gruppe. IF UNDERLYING ASSUMPTIONS PROVE INACCURATE OR UNKNOWN RISKS OR UNCERTAINTIES MATERIALIZE, ACTUAL RESULTS AND THE TIMING OF EVENTS MAY DIFFER MATERIALLY FROM THE RESULTS AND/OR TIMING DISCUSSED IN THE FORWARD-LOOKING STATEMENTS, AND YOU SHOULD NOT PLACE UNDUE RELIANCE ON THESE STATEMENTS.

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