They can give you advice and may give you creams or medicines to help. But these treatments will not increase your sex drive. Some people have indigestion or acid reflux (acid comes up from the stomach into the gullet) when taking this treatment. Rarely, these may be life-threatening. You may report side effects to the FDA at 1-800-332-1088. Instructions on how you can make a PDF version of this page using the print function on your browser. Enzalutamide (formerly known as MDV3100) is a rationally designed, targeted androgen-receptor inhibitor that competitively binds to the ligand-binding domain of … If the number of white blood cells is low, you are more likely to get an infection. During a flush, your neck and face may feel warm and look red. Or your doctor can prescribe drugs to help. Hormones are chemicals that our bodies make. Take enzalutamide at the same time of day. They can also give you ways to help manage it. You may notice changes in your memory. Talk with the doctor. Always tell your doctor or nurse about any skin changes. Almost all testosterone in men is made by the testicles. If you are having sex and your partner is pregnant, use a condom while taking enzalutamide and for 3 months after your last dose. If you have questions about side effects, call your doctor. If you feel dizzy when walking, you should sit down straight away until it passes. This medicine is not approved for use in women. The treatment may cause a rash, which may be itchy. Do not chew, break, open, or dissolve. Most men lose their sex drive and have erection problems during hormonal therapy. It can be given alone or with other types of hormonal therapy drugs. This is known as advanced (metastatic) prostate cancer. Always tell your doctor, nurse or pharmacist about any side effects you have. If you are taking any of these drugs: Alfentanil. Try to keep areas that you walk through clear to reduce the risk of tripping. Taking enzalutamide, over time, increases your risk of bone thinning (osteoporosis). Call your doctor or get medical Some drugs may have another patient information leaflet. Save these numbers in your phone or keep them somewhere safe. You may get some of the side effects we mention, but you are unlikely to get all of them. They can also tell you about treatments for bone thinning. If you feel unwell or need advice, you can call them at any time of the day or night. You can read more about coping with hot flushes and managing hormonal symptoms in our information on prostate cancer. Do not store in a bathroom. A low white blood cell count is called neutropenia. Find out more about how we use your information in our Privacy Policy and Cookie Policy. Have your blood pressure checked as you have been told by your doctor. Uncommon (0.1% to 1%): Seizures. There are things you can do to try to reduce flushes: You may have fewer hot flushes and sweats as your body adjusts to hormonal treatment. This may lead to a higher chance of getting an infection. Generic Name: Enzalutamide (en za LOO ta mide)Brand Name: Xtandi. Check with your These are common. We’ve created a new account area offering personalised cancer information and support. Applies to enzalutamide: oral capsule. For more detailed information you can visit the electronic Medicines Compendium (eMC). Very rarely, enzalutamide can cause seizures (fits). Information about your device and internet connection, including your IP address, Browsing and search activity while using Verizon Media websites and apps. Some drugs can affect whether you can make someone pregnant. to make sure that it is safe for you to take enzalutamide with all of your drugs and health problems. This means they will be more likely to work for you. Enzalutamide side effects (in more detail). Use enzalutamide as ordered by your doctor. Eating a healthy diet, not smoking and not drinking more alcohol than the recommended limit also helps to protect your bones. Whatever cancer throws your way, we’re right there with you. © Macmillan Cancer Support, registered charity in England and Wales (261017), Scotland (SC039907) and the Isle of Man (604). Have blood work checked as you have been told by the doctor. Make sure rooms are well lit and always put a light on if you get up during the night. Your doctor will advise you not to make someone pregnant while having this treatment. To enable Verizon Media and our partners to process your personal data select 'I agree', or select 'Manage settings' for more information and to manage your choices. Take a missed dose as soon as you think about it. Let your doctor know if you have any pain in your bones or joints. Contact the hospital straight away on the 24-hour contact number you have if: It is important to follow any specific advice your cancer treatment team gives you. This may slow down the growth of the cancer cells and help control advanced prostate cancer. Swallow whole. Enzalutamide is also known as Xtandi®. Here is the. We and our partners will store and/or access information on your device through the use of cookies and similar technologies, to display personalised ads and content, for ad and content measurement, audience insights and product development. Enzalutamide (Xtandi®) is a type of hormone therapy for men with prostate cancer that has spread to other parts of the body (advanced prostate cancer).It is usually only offered to men whose prostate cancer has stopped responding to other types of hormone therapy.But during the coronavirus outbreak, you may be offered enzalutamide as a first treatment for advanced prostate cancer. taken, how much, and when it happened. You must check If you have any of these signs, contact the hospital straight away. Throw away unused or expired drugs. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you are also having treatment with other cancer drugs, you may have some side effects that we have not listed here. It is important to take them exactly as your nurse or pharmacist explains. If you feel sleepy, do not drive or operate machinery. Some people feel anxious or irritable during a hot flush. This includes your doctors, nurses, pharmacists, and dentists. Do not share your drugs with others and do not take anyone else's drugs. If your skin feels dry, try using an unperfumed moisturising cream every day. If you are a woman using enzalutamide, talk with your doctor if you are pregnant, plan on getting pregnant, or are breast-feeding. Falls may lead to very bad problems like. Call your doctor right Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Talk with the doctor. Signs of a reaction include swelling of the lips, tongue, or throat. Subscribe to Drugs.com newsletters for the latest medication news, alerts, new drug approvals and more. They can give you painkillers. Let your doctor know if you are already taking medication for seizures. Your doctor can prescribe treatments to help with erection problems. advice about side effects. Available for Android and iOS devices. Registered office: 89 Albert Embankment, London SE1 7UQ. Some medicines can affect the hormonal treatment or be harmful when you are having it. Keep all drugs in a safe place. If you are a man and your sex partner gets pregnant while you take enzalutamide or within 3 months after your last dose, call your doctor There may be ways to preserve your fertility. Medivation and Astellas Pharma, the companies that manufacture and market enzalutamide, funded the study. hungry, or very bad, Low white blood cell counts have happened with enzalutamide. You may find you get restless legs while taking this treatment. Postmarketing reports: Posterior reversible encephalopathy syndrome (PRES) (e.g., … Sometimes this can increase the risk of a broken bone (fracture). Don’t drive or operate machinery if you have them. You may also report side effects at https://www.fda.gov/medwatch. Results. Always tell your dentist you are having cancer treatment. Prostate cancer needs the hormone testosterone to grow. Talk to your doctor or nurse if you get this. After your treatment is over, most side effects start to improve. In just the latest sign of just how hot new cancer drugs have become, San Francisco-based Medivation garnered a $110 million upfront payment and a … Medivation, Inc. and Astellas Pharma Inc. today announced plans to commence a Phase III clinical trial to investigate the use of enzalutamide for the treatment of triple-negative breast cancer . The number of white blood cells will usually return to normal before your next treatment. If you suddenly feel unwell, with symptoms such as worsening headache, feeling confused, or problems with your sight, contact the hospital straight away. You may have sweats then feel cold and clammy. This includes medicines you can buy in a shop or chemist. Data sources include IBM Watson Micromedex (updated 1 Oct 2020), Cerner Multum™ (updated 1 Oct 2020), … We understand that people with cancer are worried about coronavirus. during treatment and for 3 months after your last dose. At 12 months of follow-up, the rate of radiographic progression-free survival was 65 percent among men who took enzalutamide, compared with just 14 percent among men who took placebo. This treatment may cause headaches. If you think you need dental treatment, talk to your cancer doctor or nurse. But some men continue to have problems after treatment is over. Read all information given to you. Enzalutamide dosage information (in more detail). Cancer and some cancer treatments can increase the risk of a blood clot. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Rarely, enzalutamide can cause an allergic reaction. Tell your cancer doctor about any drugs you are taking, including vitamins, herbal drugs and complementary therapies. Keep all drugs out of the reach of children and pets. Store at room temperature in a dry place. Any changes to your skin are usually temporary and improve when treatment finishes. Please support our emergency appeal. Use cotton sheets and have layers of bedding. The drug may harm the developing baby. Feeling tired is a common side effect. away if you have signs of infection like fever, chills, or, A very bad and sometimes deadly brain problem called posterior reversible. Give them the contact details for your cancer doctor so they can ask for advice.
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