Rolls-Royce Group | [93] While the trial resumed in the UK, Brazil, South Africa, Japan,[94] and India, it remained in the USA on pause while the FDA investigated a patient illness that triggered the clinical hold according to the HHS Secretary Alex Azar. Zeneca (officially Zeneca Group PLC) was a British multinational pharmaceutical company headquartered in London, United Kingdom. [52][53] On 6 November it was reported that AstraZeneca acquired ZS Pharma for $2.7 billion. "[116] The court held that this was the case even if the employee "otherwise performed valuable services," and that the employee was not entitled to recover restitution for the value of those other services. AstraZeneca is a global, science-led biopharmaceutical business and our innovative medicines are used by millions of patients worldwide. In 2000 he moved to Aventis in America, becoming chief operating officer of Aventis USA in 2002, which became Sanofi Aventis USA in 2004. [44] Towards the end of April the company announced a number of collaborations worth an estimated $1.8 billion; firstly, to develop and commercialise MEDI4736, with Celgene, for use against non-Hodgkin’s lymphoma, myelodysplastic syndromes, and multiple myeloma with AstraZeneca receiving $450 million. Treated with a normal dose of the enantiomeric mixture, these persons will experience blood levels five-times higher than those with normal CYP2C19 production. AstraZeneca plc (/ˌæstrəˈzɛnəkə/) is a British (formely British-Swedish) multinational pharmaceutical and biopharmaceutical company with its global headquarters in Cambridge, United Kingdom. INO-3112 targets Human papillomavirus types 16 and 18. [69][70] However, these plans were subsequently dropped because it would have distracted the company from its own pipeline and ongoing COVID-19 vaccine efforts. The company's Medimmune arm also launched collaborative clinical trials with Juno Therapeutics, investigating combination treatments for cancer. AstraZeneca has also agreed to support the establishment of a joint research centre at Oxford University for pandemic preparedness research. Coca-Cola HBC | AstraZeneca was founded in 1999 through the merger of the Swedish Astra AB and the British Zeneca Group (itself formed by the demerger of the pharmaceutical operations of Imperial Chemical Industries in 1993). Among other things, the company was accused of having paid doctors to give speeches and publish articles (ghostwritten by the company) promoting those unapproved uses. [49] In August, the company announced it has acquired the global rights to develop and commercialise Heptares Therapeutics drug candidate HTL-1071, which focuses on blocking the adenosine A2A receptor, in a deal worth up to $510 million. RSA Insurance Group | The company agreed to pay $355 million, consisting of $64 million in criminal fines, a $266 million settlement of civil False Claims Act charges, and a $25 million settlement of fraud charges relating to state Medicaid programs. [79] Catalent will be responsible for the finishing and packaging process. This page was last edited on 4 August 2020, at 14:58. [106], In March 2011, AstraZeneca settled a lawsuit in the United States totalling $68.5 million to be divided up to 38 states. [34] In July 2014 the company entered into a deal with Almirall to acquire its subsidiary Almirall Sofotec and its lung treatments including the COPD drug, Eklira. GlaxoSmithKline | He joined Roche in 2006. "[113], On 4 February 1998, Astra USA sued Lars Bildman, its former president and chief executive officer, seeking $15 million for defrauding the company. AstraZeneca (Fusioneret 1999) Astra AB (Grundlagt 1913) Tika (Opkøbt 1939) Zeneca (fra Imperial Chemical Industries, 1993) Salick Health Care (Opkøbt 1996) Ishihara Sangyo Kaisha (am. [11] Der US-Pharmakonzern Pfizer hat den Kauf großer Teile des Antibiotika-Geschäfts von AstraZeneca angekündigt. Sandvik | Centrica | Hexagon | Randgold Resources | Mondi plc | Rio Tinto Group | [105], It was also announced that Leif Johansson would succeed Louis Schweitzer as Non-Executive chairman on 1 June 2012, three months earlier than previously announced, and would become Chairman of the Nomination and Governance Committee after (the 2012) Annual General Meeting. BP | [51] In September, Valeant licensed Brodalumab from the company for up to $445 million. [95], The following is an illustration of the company's major mergers and acquisitions and historical predecessors:[96]. In 2011 AstraZeneca settled[12] a related Seroquel case brought by state governments by agreeing to pay another $69 million. AstraZeneca | AstraZeneca ist 2018 mit 22,09 Milliarden US-Dollar Umsatz[3] und 64.600 Mitarbeitern[2] einer der größten Arzneimittelhersteller weltweit. ITV | Halma | Paddy Power Betfair | The deal on the drug known as trastuzumab deruxtecan sent shares in Japan’s Daiichi soaring 16%. 67.000 ansatte i følgende lande: Sverige 21%, USA 20%, Storbritannien 18% og resten af verden 41%. [103], On 26 April 2012 it was announced that Brennan was to retire early in the June of that year[104] In August 2012, Pascal Soriot was named CEO of AstraZeneca. [27], In March 2013 AstraZeneca announced plans for a major corporate restructuring, including the closure of its research and development activities at Alderley Park and Loughborough in the UK and at Lund in Sweden, investment of $500 million in the construction of a new research and development facility in Cambridge and the concentration of R&D in three locations: Cambridge, Gaithersburg, Maryland (location of MedImmune, where it will work on biotech drugs), and Mölndal (near Gothenburg) in Sweden, for research on traditional chemical drugs. It is a listed company and is a subsidiary of AstraZeneca Plc, UK. Subsequently, more than 25,000 lawsuits were filed against the company. NMC Health | Những trung tâm R & D của nó tập trung ở Cambridge, Gaithersburg, Maryland và Mölndal ở Thụy Điển. Royal Dutch Shell | [17] AstraZeneca's pipeline, and "patent cliff", was the subject of much speculation in April 2007 leading to pipeline-boosting collaboration and acquisition activities. [9] In December 1997, Zeneca acquired the US fungicide operations of Ishihara Sangyo Kaisha, along with the international distribution rights to four recently developed fungicides, herbicides and pest control products, for US$500 million. [5], "Zeneca" was an invented name created by the branding consultancy Interbrand. The deal was part of the Trump administration's Operation Warp Speed initiative to develop and rapidly scale production of targeted vaccines before the end of 2020. The companies had been meeting since January 2014. AstraZeneca plans to use some of the proceeds of a $3.5 billion share issue to fund the deal. Hargreaves Lansdown | We encourage you to read the privacy policy of every website you visit. Ferguson | [7], Am 2. Content is available under $1 unless otherwise noted. According to the settlement agreement, AstraZeneca targeted its illegal marketing of the anti-psychotic Seroquel towards doctors who do not typically treat schizophrenia or bipolar disorder, such as physicians who treat the elderly, primary care physicians, pediatric and adolescent physicians, and in long-term care facilities and prisons. AstraZeneca. [45] The trials will assess combinations of MEDI4736 and one of Juno Therapeutics' CD19 directed chimeric antigen receptor T-cell candidates. Cement Roadstone Holding | Antofagasta | Segro | [4] Other key products included heart drug Tenormin. [4] Im September 2019 kündigte AstraZeneca zudem an, den Produktionsstandort Wedel Ende 2021 zu schließen. AstraZeneca plc is a British–Swedish pharmaceutical company formed by the 1999 merger of the Swedish Astra AB and the British Zeneca Group. AstraZeneca provides this link as a service to website visitors. Since the merger it has been among the world's largest pharmaceutical companies and has made numerous corporate acquisitions, including Cambridge Antibody Technology (in 2006), MedImmune (in 2007), Spirogen (in 2013) and Definiens (by MedImmune in 2014). Experian | Anglo American | [121], 2007–12: The patent cliff and subsequent acquisitions, Bildman fraud, and faithless servant clawback, AstraZeneca Press Release. Pascal Claude Roland Soriot (born 23 May 1959) is the chief executive officer of the British pharmaceutical multinational company AstraZeneca, since October 2012. Getinge | svampepesticid-firma, Opkøbt 1997) KuDOS Pharmaceuticals (Opkøbt 2005) MedImmune Biologics Cambridge Antibody Technology (Opkøbt 2006) Aptein Inc (Opkøbt 1998) The deal could potentially be worth up to $6 billion for Daiichi. Boliden | When it is manufactured the result is a mixture of two mirror-imaged molecules, R and S. Two years before the omeprazole patent expired, AstraZeneca patented S-omeprazole in pure form, pointing out that since some people metabolise R-omeprazole slowly, pure S-omeprazole treatment would give higher dose efficiency and less variation between individuals. [92] AstraZeneca was criticized for vaccine safety after concerns from experts noting the company's refusal to provide details about serious neurological illnesses in two participants who received the experimental vaccine in Britain. [1][7] In 1996 he became General Manager of Hoechst Marion Roussel in Australia, moving to Tokyo in April 1997. 21 March 2013, Lemke TL, Williams DA, Roche VF, Zito SW. Foye's Principles of Medicinal Chemistry, 7th edition, Chapter 12, National Institute of Allergy and Infectious Diseases (NIAID), Pharmaceutical industry in the United Kingdom, "Registered office and corporate headquarters", "UPDATED: AstraZeneca to ax 1,600, relocate thousands in global R&D reshuffle", "AstraZeneca Selects Wilmington, Del. Any reference in these archives to AstraZeneca products or their uses may not reflect current medical knowledge and should not be used as a source of information on the present product label, efficacy data or safety data. Prudential | [6], He studied veterinary medicine at university (École nationale vétérinaire d'Alfort at Maisons-Alfort in south-east Paris). [11] He has three brothers, all of whom are doctors. SKF | Melrose Industries | 2009), applying New York's faithless servant doctrine, the court held that a company's employee who had engaged in financial misdeeds and sexual harassment must "forfeit all of his salary and bonuses for the period of disloyalty. [4] AstraZeneca has a portfolio of products for major disease areas including cancer, cardiovascular, gastrointestinal, infection, neuroscience, respiratory and inflammation.[5].
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