Yoneshiro T, Wang Q, Tajima K, Matsushita M, Maki H, Igarashi K, Dai Z, White PJ, McGarrah RW, Ilkayeva OR, Deleye Y, Oguri Y, Kuroda M, Ikeda K, Li H, Ueno A, Ohishi M, Ishikawa T, Kim K, Chen Y, Sponton CH, Pradhan RN, Majd H, Greiner VJ, Yoneshiro M, Brown Z, Chondronikola M, Takahashi H, Goto T, Kawada T, Sidossis L, Szoka FC, McManus MT, Saito M, Soga T, Kajimura S, Lindtner S, Catta-Preta R, Tian H, Su-Feher L, Price JD, Dickel DE, Greiner V, Silberberg SN, McKinsey GL, McManus MT, Pennacchio LA, Visel A, Nord AS, Rubenstein JLR, Gagnon JD, Kageyama R, Shehata HM, Fassett MS, Mar DJ, Wigton EJ, Johansson K, Litterman AJ, Odorizzi P, Simeonov D, Laidlaw BJ, Panduro M, Patel S, Jeker LT, Feeney ME, McManus MT, Marson A, Matloubian M, Sanjabi S, Ansel KM, Wang TA, Teo CF, Åkerblom M, Chen C, Tynan-La Fontaine M, Greiner VJ, Diaz A, McManus MT, Jan YN, Jan LY, Mues M, Karra L, Romero-Moya D, Wandler A, Hangauer MJ, Ksionda O, Thus Y, Lindenbergh M, Shannon K, McManus MT, Roose JP, ©2020 The Regents of the University of California, Noncoding RNAs - the Dark Matter of the Genome. will be bypassed and you will receive a single individual's record. California San Francisco. We take high-throughput approaches, analyzing hundreds of thousands to millions of experiments at once, using unique and complex libraries coupled to deep sequencing. Secondary Phone. large selection of preformed campus addresses. Michael.McManus@ucsf.edu Telephone (415) 476-4661 Box 0534. While Dr. McManus choose to make the move to UCSF because of its renowned and highly collaborative medical science community, he was also lured west for personal reasons. In general, the longer your Thank you for your continued support. Address. 513 Parnassus Ave, HSW, 1047A San Francisco, CA 94143 . This flexibility We look forward to providing you with even more cutting-edge market research, as Topio Networks. Applying systems biology approaches to human disease models. In addition, more than a hundred mouse small RNA knockout models are being made in the lab. For departmental information, click on the “Search for Information Practices Act, this directory may not be used, rented, large departments, this directory may not even display all of the results. information in mailing lists and telephone directories We believe that the regulatory noncoding RNAs that have been discovered are just the 'tip of the iceberg' in a set of important biology that we are far from understanding. High-Complexity shRNA Libraries and PI3 Kinase Inhibition in Cancer: High-Fidelity Synthetic Lethality Predictions. Learn more about Michael McManus, PhD, Member, Diabetes Center, UCSF including contact information, career history, news and intelligence. We would like to understand the pathways and mechanisms of small RNAs, and develop technologies that will improve our efforts to intersect human disease. department listing please open a ticket at help.ucsf.edu, or contact the IT Service Desk at (415) 514-4100. Since our “City by the Bay” is well-known for both its culture and the arts, it is a perfect home for Dr. McManus and his wife, Jennifer, who is by training a professional ballerina! For example, searching for cardio would return departments with names Our lab embraces genome-scale function-based screening and other high-throughput methodologies to uncover gene function in the mammalian system. for more details. will contain physical addresses, website address, phone numbers, fax numbers and other department location enables you to use a partial or whole department name to find all the members of a given department. Please see the You can use this site to find contact information for people and departments affiliated with UCSF. information in mailing lists and telephone directories. department within the department search tab yields departmental information. After logging in you will be presented with the edit page for We aim to uncover the dark matter of the genome, to help unravel the beautiful genomic complexity of pathways and how genes interact in development and disease. miR-15/16 Restrain Memory T Cell Differentiation, Cell Cycle, and Survival. departments” tab. behave the same when viewing an individual record. The links mentioned above Core Manager: Jennifer Page, Ph.D. Genentech Hall N214 600 16th Street San Francisco, CA 94158 Campus mailbox: 2202 Phone: 415-502-3387 We are interested in applying high-throuput and systems/synthetic biology to fundamental problems in health and disease. Michael McManus, PhD | Biomedical Sciences Graduate Program ... Michael T. McManus, Ph.D. | UCSF Diabetes Center. Those with a campus address may choose from a The McManus lab studies fundamental processes relating to the regulation of gene expression. The lab has efforts towards understanding how microRNAs contribute to the specification of cell fate, and how disregulation of microRNAs may contribute to human disease. We operate in a diversity of research areas- including RNA biology and developing cutting-edge research tools based on RNA biology— to answer fundamental biological questions. self-service section of the directory website. For some very general searches, especially for University guidelines for assuring privacy of personal If you enjoy performing cutting-edge interdisciplinary research in an exciting and highly collaborative environment, please apply to our lab. Your search term(s) will match departments by department name. Director, Keck Center for Noncoding RNAs To search for a person by name you may use all or part of his or her name. Sharp. search term is, the narrower your results will be. people search tab returns information regarding people related to the given department, searching by Once on the desired search tab, enter your search term into the input field above the Department listing information may only be edited by directory administrators. Note "joe." Campus Office Address. It will, however, find people named Joel or Joey. UCSF, Tue, Nov 08, 2011 by Anonymous user from 12.144.x.x, Associate Professor, Department of Microbiology and Immunology, review about microRNA and knockout mice (Nov-2011), JEM interview of Michael McManus (Mar-2008). blue button and then click the button. BCAA catabolism in brown fat controls energy homeostasis through SLC25A44. and contact information. Mickie Cheng : M_Diabetes Center : Mickie.Cheng@ucsf.edu (415) 502-9581: Box 0540 : Toggle navigation × Close Mickie Cheng. Phone (415) 476-4661. that searching for a department name within the “Search for people” tab does not provide department you might try including a last initial or a department name. Private practice address information must be initially entered by Human Resources, your Based on our studies of this biology, we have developed tools and agents that usurp this pathway for the interrogation of gene function and the potential use in the intervention of human disease. The McManus lab studies fundamental processes relating to the regulation of gene expression. Our studies add significantly to our understanding of how cells react to their environments and will shed new insight into genomic noncoding RNA dark matter. is case-insensitive. In that case, you will see a Be specific. Dr. McManus was awarded his PhD in Biochemistry and Molecular Genetics at the University of Alabama Birmingham. Click on a person’s department name to find all people within that Based on our studies of this biology, we have developed cutting-edge research tools and agents that usurp this pathway for the interrogation of gene function and the potential use in the intervention of human disease. From there you will be able to edit your entire directory entry except for your last Our group contains outstanding scientists from highly diverse fields including developmental biology, immunology, neurobiology, cancer, and biophysics. Systematically deconvoluting molecular networks of coding and noncoding genes. We welcome trainees that are interesting making use of the above systems to help us understand the exciting world of noncoding RNA. The results All searching, whether for people or departmental information, To search To search for a department, first be sure you have selected the Search for departments tab. name to see their individual record. Contact the Service Desk online, or phone 415-514-4100, University guidelines for assuring privacy of personal Curated profile of Michael McManus, PhD, Director, Keck Center for Noncoding RNAs, UCSF including career history, news and intelligence, portfolio companies and … like Cardiology, Cardiovascular, Cardiothoracic, etc. View Michael McManus’ profile on LinkedIn, the world's largest professional community. We develop new technologies to address unmet challenges and advance science in leaps and bounds through collaboration. Thermoregulation via Temperature-Dependent PGD2 Production in Mouse Preoptic Area. listed herein, in accordance with the State of California This campus directory is the property of the University of Our lab is interested in understanding how noncoding RNAs contribute to the specification of cell fate and function, and how deregulation of these RNAs may contribute to human disease. name, title, department and email address. To date only a handful of noncoding RNAs have been functionally characterized. Our systems span from cell culture to in vivo models, focusing on a broad array of disease relevant tissues. Michael.McManus@ucsf.edu. We are particularly excited about a new method we developed to rapidly screen for gene function in mammalian cells— using RNAi libraries and deep sequencing to dissociate members of functional pathways. Life depends on genetically encoded networks to help make sophisticated decisions influenced by the environment. Michael has 3 jobs listed on their profile. In an effort to understand the broad biological significance of noncoding RNAs, we have knocked out large numbers of them in mouse models. Genomic Resolution of DLX-Orchestrated Transcriptional Circuits Driving Development of Forebrain GABAergic Neurons.
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